N S Lab Members

PRESENT LAB MEMBERS:

Our email addresses are of the form "user@mbu.iisc.ernet.in"

Ashraya Ravikumar

ashraya

PhD student, IISc
B.E. Computer Science and Engg, SSN College of Engineering-Anna University, Chennai

My projects are aimed towards understanding stereochemistry of proteins and peptides and applications to protein structure determination and validation. I am also particularly interested in studying functionally important strained conformations found in proteins.

Gayatri Kumar

gayatrikumar

Graduate Student
M.Sc, Biotechnology, Jain University, Bangalore.

I am attempting to use protein like artificial sequences to bridge the gap between sequence and structural domains. Using the design strategy developed in our lab, artificial protein like sequences, intermediately relating SCOP families were generated in an attempt towards remote homology detection. In an attempt to give structural cues for sequence families without structural information I am employing designed sequences in my study. I am also, interested in studying the energy landscape of these artificial sequences and whether they adopt the fold of the parent SCOP families. Future prospects involve, exploring the unchartered fold space using both the undirected and directed sequence design approaches developed in the group.

Himani Tandon

himanit

Graduate Student,
M.Sc. Bioinformatics, Pondicherry University, Pondicherry.

Janaki Ch

janaki

Graduate Student, under External Registration Programme (ERP).
M.Sc, Genetics,Advance Diploma in Bioinformatics, Principal Technical Officer, C-DAC, Bengaluru.

I am working on developing computational methods for detecting remote homologues of proteins. To gain better insights into the protein structure and function, I study evolutionary relationships between protein families, superfamilies and folds through large-scale data analysis using high performance computing clusters.

Naveen Kumar N

nkumar

Research Assistant of Dr. R. Sowdhamini, NCBS, Bangalore. Collaboration with
Prof. N. Srinivasan, IISc, Bangalore
M.Sc, (Bioinformatics),University of Madras, Chennai.

Understanding the functional relevance of asymmetry in heterodimeric proteins. Symmetric form often confers stability and prevalent in oligomeric proteins but mild pertubation from symmetry will be essential for dynamic functions.

Prasanth kumar

prasanth

Post-Doctoral Fellow,
IISc DBT-PDF,
Ph.D., Gujarat University,
M.Sc., Alagappa University .

Protein-Ligand interactions.

Sandhya Sankaran

sandhya

Research Associate,
Ph.D., Manipal University,
M.Sc., Biotechnology, Pondicherry University, Pondicherry.

Sneha Vishwanath

snehav

Integrated PhD Student
BSc.(Hons.)Chemistry, St.Stephen's College, Delhi University

The questions addressed by me, revolve around modular interactions involving both protein-protein interactions as well as domain-domain interactions. The first project focused on the evolution of interface of proteases-inhibitor complexes. The second project revolves around the structural changes associated with the absence of tethered domain in multi-domain proteins.

Sohini Chakraborti

sohini

Graduate Student
M.S. (Pharm) in Pharmacoinformatics, National Institute of Pharmaceutical Education and Research, Hajipur (Ministry of Chemicals & Fertilizers, Dept. of Pharmaceuticals, Govt. of India).

Srinivasan N.

ns

Head
Ph.D., Indian Institue of Science
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Yazhini Arangasamy

yazhinia

PhD student, IISc
B.Tech (Biotech), PSG Tech-Anna University

My research strives to improve our understanding of structural and mechanistic attributes of macromolecular complexes through sequence homology. Also, it involves the probing of genomic data to identify species specific features by comparative sequence analysis.

Saranaya Marimuthu

saranya

Graduate Student with Asst.Prof Rahul Roy, Chemical Engineering IISc Bangalore
B.Tech Biotechnology,National Institute of Technology, Calicut